

N-ALKYLATION OF NITROGEN HETEROCYCLES WITH α-DIAZOCARBONYL COMPOUNDS

Abstract
Examples of the use of α-diazocarbonyl compounds in the N–H insertion reactions with the formation of the products of selective N-alkylation of various five-membered nitrogen heterocycles and their derivatives are considered. The literature data is systematized according to the number of N atoms in the heterocycle. The review contains information published in the period from 2003 to 2020.
Authors: Igor V. Solovyev, Daniil D. Zhukovsky, Dmitry V. Dar'in, Mikhail Yu. Krasavin*
N-alkylation of various five-membered nitrogen heterocycles and their derivatives are considered. The literature data is systematizedaccording to the number of N atoms in the heterocycle. The review contains information published in the period from 2003 to 2020.
Keywords
азотистые гетероциклы; α-диазокарбонильные соединения; алкилирование; внедрение по связи N–H
Latvian Institute of Organic Synthesis - Aizkraukles iela, 21, Riga, LV-1006, Latvia - hgs@osi.lv