N-ALKYLATION OF NITROGEN HETEROCYCLES WITH α-DIAZOCARBONYL COMPOUNDS

Abstract

Examples of the use of α-diazocarbonyl compounds in the N–H insertion reactions with the formation of the products of selective N-alkylation of various five-membered nitrogen heterocycles and their derivatives are considered. The literature data is systematized according to the number of N atoms in the heterocycle. The review contains information published in the period from 2003 to 2020.

Authors: Igor V. Solovyev, Daniil D. Zhukovsky, Dmitry V. Dar'in, Mikhail Yu. Krasavin*

N-alkylation of various five-membered nitrogen heterocycles and their derivatives are considered. The literature data is systematized
according to the number of N atoms in the heterocycle. The review contains information published in the period from 2003 to 2020.