RECENT ADVANCES IN DEAROMATIZATION OF BENZAZOLES, PURINES, AND CAFFEINE

Abstract

Dearomatization reactions are well established in organic synthesis and other research fields usually leading to structurally diverse polycyclic molecules or complex heterocyclic frameworks. In this microreview, recent development of dearomative functionalization of benzazoles, purines, and caffeine via cycloaddition or addition reaction has been summarized. This will help researchers to find the potential scientific value of dearomatization reactions in drug discovery.