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SYNTHESIS OF JULOLIDINE DERIVATIVES via SNCl4-PROMOTED SPIROCYCLIZATION OF (1-ALKYLTETRAHYDROQUINOLIN-8-YL)METHYLIDENE-1H-IMIDAZOL-5(4H)-ONES

Василисса В. Широкова, Александр Ю. Смирнов, Эльвира Р. Зайцева, Надежда С. Балеева, Андрей А. Михайлов, Михаил С. Баранов
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Abstract


(1-Alkyltetrahydroquinolin-8-yl)methylidene-1H-imidazol-5(4H)-ones undergo spirocyclization by the action of SnCl4 via 1,5-hydride shift to form spirocyclic julolidine derivatives in 68–97% yields.

Keywords


imidazole; julolidine; tetrahydroquinoline; 1,5-hydride shift; spirocyclic compounds.

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