2-(2-FURYL)IMIDAZO[1,2-a]PYRIMIDINE SYNTHESIS AND ELECTROPHILIC SUBSTITUTION REACTIONS

Abstract

The synthesis of 2-(2-furyl)imidazo[1,2-a]pyrimidine has been carried out. Azocoupling,  nitrosation, and bromination by 1 mole of bromine occur at position 3 of the bicycle. Reaction with 2 mol of bromine gives the 3,5'-disubstituted derivative. Bromination  using 1 mol of bromine in 40% hydrobromic acid and sulfonation occur initially at the 5' position of the furyl group.

How to Cite
Saldabol, N.; Popelis, J.; Lando, O.; Slavinska, V.  Chem. Heterocycl. Compd. 2006, 42, 495. [Khim. Geterotsikl. Soedin. 2006, 565.]

For this article in the English edition, see DOI 10.1007/s10593-006-0116-0