PREPARATION OF <i>N</i>-PHENYLBENZO[<i>h</i>]QUINOLINIUM DERIVATIVES LABELED WITH TRITIUM

Authors

  • Н. Е. Щепина Natural Science Institute, Perm State National Research University
  • В. В. Аврорин Saint Petersburg State University
  • Г. А. Бадун Moscow M. V. Lomonosov State University
  • И. И. Бойко "Technolog Co. Ltd"

DOI:

https://doi.org/10.1007/1011

Keywords:

nucleogenic phenyl cations, N-phenylbenzo[h]quinolinium salts, tritiated biological markers, nuclear-chemical synthesis

Abstract

The possibility of a direct phenylation of benzoquinoline nitrogen atom with nucleogenic phenyl cations has been demonstrated. A simple method has been developed for obtaining previously unknown tritium labeled N-phenyl derivatives of benzo[h]quinolinium, which are promising radioactive markers for studying the biological action mechanisms of medicinal substances containing the benzoquinolinium structure.

Authors: N. E. Shchepina, V. V. Avrorin, G. A. Badun, and I. I. Boiko

English Translation in Chemistry of Heterocyclic Compounds, 2012, 48 (8), pp 1196-1199

http://link.springer.com/article/10.1007/s10593-012-1121-0

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Published

2013-10-15

Issue

No. 8 (2012)

Section

Original Papers