Synthesis, structure, and biological activity of [2.2]paracyclophanes. 7. Synthesis of 2-([2.2]paracyclophan-4-yl)pyridines,-tetrahydroquinolines, and-benzo[<i>h</i>]quinolines based on condensation of 4-(β-dimethylaminopropionyl)[2.2]paracyclophane with primary amines

Abstract

Condensation of 4-(β-dimethylaminopropionyl)paracyclophane with aliphatic aldehydes or cyclohexanones in the presence of hydroxylamine gave 2-([2.2]paracyclophan-4-yl)pyridines and -5,6,7,8-tetrahydroquinolines respectively. Reaction of these salts with α-naphthylamine gives a mixture of paracyclophanyl substituted 1,2,3,4-tetrahydrobeno[h]quinoline and benzo[h]quinoline.

How to Cite
Kryvenko, L. I., Soldatova, S. A.; Zvolinskii, O. V.; Romanenko, E. E., Struchkova, M. I.; Soldatenkov, A. T. Chem. Heterocycl. Compd. 1997, 33, 933. [Khim. Geterotsikl. Soedin. 1997, 1069.]

For this article in the English edition, see DOI https://doi.org/10.1007/BF02253164