Synthesis and alkylation of 6-methyl-5-phenylcarbamoyl-3-cyano-4-ethylpyridine-2(1H)-thione

Authors

  • В. Д. Дяченко T. G. Shevchenko Lugansk State Pedagogical Institute, Lugansk 348011
  • С. Г. Кривоколыско T. G. Shevchenko Lugansk State Pedagogical Institute, Lugansk 348011
  • В. П. Литвинов N. D. Zelinskii Institute of Organic Chemistry, Russian Academy of Sciences, 117913 Moscow

Abstract

By condensation of the anilide of acetoacetic acid, propionaldehyde, and cyanothioacetamide, 6-methyl-5-phenylcarbamoyl-3-cyano-4-ethylpyridine-2(1H)-thione has been obtained. In an alkaline medium, this compound is alkylated, forming the corresponding substituted 2-pyridyl sulfides. From these pyridines, substituted thieno[2,3-b]pyridines have been synthesized through the Thorpe-Ziegler reaction.

How to Cite
Dyachenko, V. D.; Krivokolysko, S.G.; Litvinov, V. P. Chem. Heterocycl. Compd. 1996, 32, 1055. [Khim. Geterotsikl. Soedin. 1996, 1232.]

For this article in the English edition, see DOI https://doi.org/10.1007/BF01164712

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Published

1996-09-25

Issue

No. 9 (1996)

Section

Original Papers