Simple and effective method for the synthesis of 3′,5′-substituted 1-β-D-arabinofuranosyluracil

Abstract

3′,5′-Substituted arabinofuranosyluracil is a starting compound in 2′-modifications. A convenient and effective method is proposed for the synthesis of 1-(3′,5′-di-o-trityl-β-D-arabinofuranosyl)uracil by successive reactions of 2,2′-cyclization of uridine, 3′,5′-tritylation of the 2,2′-anhydrouridine, and hydrolytic cleavage of the 2,2′-anhydro bond.

How to Cite
Zablotskaya, A.; Segal, I.; Pedersen, E. V. Chem. Heterocycl. Compd. 1996, 32, 835. [Khim. Geterotsikl. Soedin. 1996, 975.]

For this article in the English edition, see DOI https://doi.org/10.1007/BF01165730