Pyrrolopyrimidines. 1. Electrophilic substitution reactions of 1,3-dimethylpyrrolo[3,2-<i>d</i>]pyrimidine-2,4-dione

Authors

  • Е. Б. Цупак Rostov State University, Rostov-on-Don 344090
  • Ю. H. Ткаченко Rostov State University, Rostov-on-Don 344090
  • А. Ф. Пожарский Rostov State University, Rostov-on-Don 344090

Abstract

The reactions of halogenation, aminomethylation, acylation, and azo coupling in 1,3-dimethylpyrrolo[3,2-d]pyrimidine-2,4 dione proceed at position 7, whereas nitration in acetic acid is directed primarily to position 6. In a some of cases, products of substitution of both hydrogen atoms in the pyrrole ring have been synthesized.

How to Cite
Tsupak, E. B.; Tkachenko, Yu. N.; Pozharskii, A. F. Chem. Heterocycl. Compd. 1994, 30, 1077. [Khim. Geterotsikl. Soedin. 1994, 1242.]

For this article in the English edition, see DOI https://doi.org/10.1007/BF01171169

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Published

2026-05-14

Issue

No. 9 (1994)

Section

Original Papers