Synthesis and properties of 4-haloimidazo[4,5-<i>c</i>]pyridin-2-ones

Authors

  • Ю. М. Ютилов L. M. Litvinenko Institute of Physical Organic and Coal Chemistry, National Academy of Sciences of Ukraine, 340114 Donetsk
  • И. А. Свертилова L. M. Litvinenko Institute of Physical Organic and Coal Chemistry, National Academy of Sciences of Ukraine, 340114 Donetsk

Abstract

The nitro group in 4-nitroimidazo[4,5-c]pyridin-2-ones is rather labile and may be replaced upon heating with hydrohalic acids to give the corresponding 4-halides. A methyl group at N(3) leads to a sharp increase in the lability of the nitro group, but the isomeric 5-nitro derivatives do not react with hydrobromic or hydrochloric acids. Some reactions and transformations of 4-chloroimidazo[4,5-c]pyridin-2-one are examined.

How to Cite
Yutilov, Yu. M.; Svertilova, I. A. Chem. Heterocycl. Compd. 1994, 30, 923. [Khim. Geterotsikl. Soedin. 1994, 1071.]

For this article in the English edition, see DOI https://doi.org/10.1007/BF01165030

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Published

1994-08-25

Issue

No. 8 (1994)

Section

Original Papers