Synthesis, structure, and chemical properties of some N-(3-chloro-2-quinoxalyl)arylsulfonamides

Abstract

We have developed a method for synthesis of N-(3-chloro-2-quinoxalyl)sulfonamides by reaction of 2,3-dichloroquinoxaline with substituted arylsufonamides. Based on the IR spectra, we have established that in the solid state, the synthesized compounds exist in the form of amide tautomers. Alkylation of these compounds leads to N-metlhyl-N-(3-chloro-2-quinoxalyl)arylsulfonamides. We demonstrate the possibility of nucleophilic substitution of the halogen upon treatment with O- and N-nucleophiles. The use of bifunctional nucleophiles leads to condensed quinoxalines.

How to Cite
Litvinenko, S. V.; Savich, V. I.; Bobrovnik, L. D. Chem. Heterocycl. Compd. 1994, 30, 340. [Khim. Geterotsikl. Soedin. 1994, 387.]

For this article in the English edition, see DOI https://doi.org/10.1007/BF01165702