SYNTHESIS OF 6-ARYL-SUBSTITUTED AZOCINO[5,4-<i>b</i>]INDOLES FROM 1-ARYL-SUBSTITUTED 2-ETHYLTETRAHYDRO-β-CARBOLINES

Authors

  • Л. Г. Воскресенский Peoples' Friendship University of Russia
  • Т. Н. Борисова Peoples' Friendship University of Russia
  • Т. М. Червякова Peoples' Friendship University of Russia
  • А. А. Титов Peoples' Friendship University of Russia
  • А. В. Козлов Peoples' Friendship University of Russia
  • Е. А. Сорокина Peoples' Friendship University of Russia
  • Р. Самавати Peoples' Friendship University of Russia
  • А. В. Варламов Peoples' Friendship University of Russia

DOI:

https://doi.org/10.1007/1681

Keywords:

activated alkynes, azocinoindoles, domino reaction, ring expansion

Abstract

We optimized the reaction of tetrahydropyridine ring expansion in 1-aryl-substituted tetrahydro-β‑carbolines by the action of activated alkynes and achieved higher than 70% yields of the target indoloazocines. The substituents in the 1-aryl ring and at the indole nitrogen atom were shown to affect the rate and selectivity of this transformation.

How to Cite
Voskressensky, L. G.; Borisova, T. N.; Chervyakova, T. M.; Titov, A. A.; Kozlov, A. V.; Sorokina, E. A.; Samavati, R.; Varlamov, A. V. Chem. Heterocycl. Compd. 2014, 50, 658. [Khim. Geterotsikl. Soedin. 2014, 716.]

For this article in the English edition see DOI 10.1007/s10593-014-1518-z

Author Biography

Л. Г. Воскресенский, Peoples' Friendship University of Russia

Organic Chemistry Department, professor

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Published

2014-06-01

Issue

No. 5 (2014)

Section

Original Papers