SYNTHESIS OF 4-ACYL-3-AMINOFURAZANS FROM 3,4-DIACYLFUROXANS
DOI:
https://doi.org/10.1007/1818Keywords:
furazan, furoxan, one-pot synthesis, 1H and 13С NMR spectroscopy, X-ray structural analysiAbstract
It was shown that 3,4-diaroylfuroxans are transformed into the corresponding 3-amino-4-aroyl- furazans by heating in aqueous ammonia. The developed one-pot methodology for the synthesis of 3‑amino-4-aroylfurazans involved the interaction of the corresponding acetophenones with nitric acid followed by treatment of the in situ formed furoxans with ammonia at elevated temperature. The structures of the obtained furazans were confirmed by IR, as well as by 1H and 13C NMR spectroscopy, and X-ray structural analysis was performed for 3-amino-4-(4-methoxybenzoyl)furazan.
How to Cite
Sheremetev, A. B.; Zabusov, S. G.; Tukhbatshin, T. R.; Palysaeva, N. V.; Suponitsky, K. Yu. Chem. Heterocycl. Compd. 2014, 50, 1154. [Khim. Geterotsikl. Soedin. 2014, 1250.]
For this article in the English edition see DOI 10.1007/s10593-014-1576-2
