<i>N</i>-(ALKOXY)- AND <i>N</i>-(ACYLOXY)PHTHALIMIDES IN ORGANIC SYNTHESIS: FREE RADICAL SYNTHETIC APPROACHES AND APPLICATIONS

Authors

  • Alexander S. Budnikov N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, 47 Leninsky Ave., Moscow 119991, Russia
  • Igor B. Krylov N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, 47 Leninsky Ave., Moscow 119991, Russia

DOI:

https://doi.org/10.1007/5482

Keywords:

N-hydroxypthalimide, cross-dehydrogenative coupling, free radicals, photoredox catalysis

Abstract

The microreview covers selected examples of the free radical cross-dehydrogenative C–O coupling of various CH reagents with N-hydroxyphthalimide leading to N-(alkoxy)- and N-(acyloxy)phthalimides.
Synthetic applications of the latter associated with the cleavage of N–O bond leading to the O-, N- and C-centered free radicals are also reviewed.

Author Biography

Igor B. Krylov, N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, 47 Leninsky Ave., Moscow 119991, Russia

Laboratory for Studies of Homolytic Reactions, PhD, Senior Researcher

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Published

2020-01-31

Issue

Vol. 56 No. 1 (2020)

Section

Heterocycles in Focus