SYNTHESIS OF 2-(3-FURYL)-1H-BENZIMIDAZOLES FROM 2-PHENACYL-1H-BENZIMIDAZOLES

Authors

  • И. Б. Дзвинчук Institute of Organic Chemistry, National Academy of Sciences of Ukraine, Kiev 02094
  • М. О. Лозинский Institute of Organic Chemistry, National Academy of Sciences of Ukraine, Kiev 02094

DOI:

https://doi.org/10.1007/7334

Keywords:

benzimidazoles, phenacyl bromides, furans, C-alkylation, selectivity, cyclocondensation

Abstract

C-Alkylation at the active methylene group of 2-phenacyl-1H-benzimidazoles with phenacyl bromides proceeds highly selectively with the formation of the corresponding 1,4-diketones, which on heating with hydrochloric acid are cyclized with the formation of the previously unknown 2-(2,5-diaryl-3-furyl)-1H-benzimidazoles.

How to Cite
Dzvinchuk, I .B.; Lozinskii, M. O.  Chem. Heterocycl. Compd. 2007, 43, 1390. [Khim. Geterotsikl. Soedin. 2007, 1637.]

For this article in the English edition see DOI 10.1007/s10593-007-0215-6


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Published

2023-01-18

Issue

No. 11 (2007)

Section

Original Papers