4-HYDROXY-2-QUINOLONES. 123. AMIDATION OF 2-BROMOMETHYL-5-OXO-1,2-DIHYDRO-5H-OXAZOLO[3,2-<i>a</i>]QUINOLINE-4-CARBOXYLIC ACID

Authors

  • И. В. Украинец National University of Pharmacy, Kharkiv 61002
  • Н. Л. Березнякова National University of Pharmacy, Kharkiv 61002
  • А. В. Туров Taras Shevchenko National University, Kiev 01033
  • С. В. Шишкина STC Institute for Single Crystals, National Academy of Sciences, Kharkiv 61001

DOI:

https://doi.org/10.1007/7449

Keywords:

oxazolo[3, 2-a]quinoline, 4-chloro-2-quinolinone, amidation, ring closing, X-ray analysis

Abstract

The reaction of 2-bromomethyl-5-oxo-1,2-dihydro-5H-oxazolo[3,2-a]quinoline-4-carboxylic acid with thionyl chloride is accompanied by atransformation of the oxazoloquinolone ring to give 4-chloro-1-(2,3-dichloropropyl)-2-oxo-1,2-dihydroquinoline-3-carboxylic acid chloride.

How to Cite
Ukrainets, I. V.; Bereznyakova, N. L.; Turov, A. V.; Shishkina, S. V.  Chem. Heterocycl. Compd. 2007, 43, 871. [Khim. Geterotsikl. Soedin. 2007, 1034.]

For this article in the English edition see DOI 10.1007/s10593-007-0138-2


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Published

2023-02-13

Issue

No. 7 (2007)

Section

Original Papers