Dipyrrolo[1,2-<i>a</i>; 2′,1′-<i>c</i>]pyrazines. 4. Aminomethylation of alkyl substituted dipyrrolo[1,2-<i>a</i>; 2′,1′-<i>c</i>]pyrazines and 5,6-dihydrodipyrrolo[1,2-<i>a</i>; 2′,1′-<i>c</i>]pyrazines

Authors

  • B. И. Теренин M. V. Lomonosov State University, Moscow 119899
  • E. Л. Рyчкинa M. V. Lomonosov State University, Moscow 119899
  • А. П. Плешкова M. V. Lomonosov State University, Moscow 119899
  • Ю. Г. Бyндель M. V. Lomonosov State University, Moscow 119899

Abstract

We have studied the aminomethylation reaction of alkyl substituted dipyrrolo[1,2-a; 2′,1′-c]pyrazines and their 5,6-dihydro analogs using different aminomethylating agents. Use of alkoxydialkylaminomethanes (aminoacetals) as Mannich reagents leads to the highest yields of the aminomethylated dipyrrolopyrazines. The compounds prepared have been studied by mass spectrometry.

How to Cite
Terenin, V. I.; Ruchkina, E. L.; Pleshkova, A. P.; Bundel', Yu. G. Chem. Heterocycl. Compd. 1998, 34, 822. [Khim. Geterotsikl. Soedin. 1998, 34, 949.]

For this article in the English edition, see DOI https://doi.org/10.1007/BF02251690

Published

1998-07-25

Issue

Section

Original Papers