Dipyrrolo[1,2-<i>a</i>; 2′,1′-<i>c</i>]pyrazines. 4. Aminomethylation of alkyl substituted dipyrrolo[1,2-<i>a</i>; 2′,1′-<i>c</i>]pyrazines and 5,6-dihydrodipyrrolo[1,2-<i>a</i>; 2′,1′-<i>c</i>]pyrazines
Abstract
We have studied the aminomethylation reaction of alkyl substituted dipyrrolo[1,2-a; 2′,1′-c]pyrazines and their 5,6-dihydro analogs using different aminomethylating agents. Use of alkoxydialkylaminomethanes (aminoacetals) as Mannich reagents leads to the highest yields of the aminomethylated dipyrrolopyrazines. The compounds prepared have been studied by mass spectrometry.
How to Cite
Terenin, V. I.; Ruchkina, E. L.; Pleshkova, A. P.; Bundel', Yu. G. Chem. Heterocycl. Compd. 1998, 34, 822. [Khim. Geterotsikl. Soedin. 1998, 34, 949.]
For this article in the English edition, see DOI https://doi.org/10.1007/BF02251690