SYNTHESIS OF ETHYL 5-ACETYL-1-R-4-ARYL-6-HYDROXY-6-METHYL-2-OXOPIPERIDINE-3-CARBOXYLATES
DOI:
https://doi.org/10.1007/855Keywords:
arylidene acetylacetone, ethoxycarbonylacetamide, piperidine, heterocyclizationAbstract
The reaction of arylidene acetylacetones and ethoxycarbonylacetamides in the presence of triethyl-amine was found to lead to the formation of ethyl 5-acetyl-1-R-4-aryl-6-hydroxy-6-methyl-2-oxo-piperidine-3-carboxylates.
Authors: M. S. Sargsyan, S. S. Hayotsyan, A. Kh. Khachatryan, A. E. Badasyan, G. A. Panosyan, and S. G. Kon'kova
English Translation in Chemistry of Heterocyclic Compounds, 2013, 48 (12), pp 1805-1808
http://link.springer.com/article/10.1007/s10593-013-1212-6