SYNTHESIS OF ETHYL 5-ACETYL-1-R-4-ARYL-6-HYDROXY-6-METHYL-2-OXOPIPERIDINE-3-CARBOXYLATES

Authors

  • М. С. Саргсян Institute of Organic Chemistry of the Scientific Technological Center of Organic and Pharmaceutical Chemistry, National Academy of Sciences of the Republic of Armenia
  • С. С. Айоцян Institute of Organic Chemistry of the Scientific Technological Center of Organic and Pharmaceutical Chemistry, National Academy of Sciences of the Republic of Armenia
  • А. Х. Хачатрян Institute of Organic Chemistry of the Scientific Technological Center of Organic and Pharmaceutical Chemistry, National Academy of Sciences of the Republic of Armenia
  • А. Э. Бадасян Institute of Organic Chemistry of the Scientific Technological Center of Organic and Pharmaceutical Chemistry, National Academy of Sciences of the Republic of Armenia
  • Г. А. Паносян Molecular Structure Research Center of the Scientific Technological Center of Organic and Pharmaceutical Chemistry, National Academy of Sciences of the Republic of Armenia
  • С. Г. Конькова Institute of Organic Chemistry of the Scientific Technological Center of Organic and Pharmaceutical Chemistry, National Academy of Sciences of the Republic of Armenia

DOI:

https://doi.org/10.1007/855

Keywords:

arylidene acetylacetone, ethoxycarbonylacetamide, piperidine, heterocyclization

Abstract

The reaction of arylidene acetylacetones and ethoxycarbonylacetamides in the presence of triethyl-amine was found to lead to the formation of ethyl 5-acetyl-1-R-4-aryl-6-hydroxy-6-methyl-2-oxo-piperidine-3-carboxylates.

Authors: M. S. Sargsyan, S. S. Hayotsyan, A. Kh. Khachatryan, A. E. Badasyan, G. A. Panosyan, and S. G. Kon'kova

English Translation in Chemistry of Heterocyclic Compounds, 2013, 48 (12), pp 1805-1808

http://link.springer.com/article/10.1007/s10593-013-1212-6

Published

2013-08-20

Issue

Section

Original Papers