SELECTIVE RECYCLIZATION OF 2-AROYLMETHYL-1H-BENZIMIDAZOLE HYDRAZONES BY CONDENSATION WITH DIMETHYLFORMAMIDE

Authors

  • И. Б. Дзвинчук Institute of Organic Chemistry, Ukrainian Academy of Sciences, Kiev 253660
  • А. В. Выпирайленко Institute of Organic Chemistry, Ukrainian Academy of Sciences, Kiev 253660
  • М. О. Лозинский Institute of Organic Chemistry, Ukrainian Academy of Sciences, Kiev 253660

Keywords:

benzimidazoles, hydrazones, pyrazoles, condensation, recyclization, selectivity

Abstract

2-Aroylmethyl-1H-benzimidazole hydrazones are converted to 1-[pyrazol-3(5)-yl]benzimidazoles by refluxing in dimethylformamide in the presence of trifluoroacetic acid. The same products are obtained by refluxing 2-aroylmethyl-1H-benzimidazoles with hydrazine hydrochloride in dimethylformamide. Electron donor substituents in the para position of the aryl fragment of the starting compounds do not favor the reaction.

How to Cite
Dzvinchuk, I. B.; Vypirailenko, A. V.; Lozinskii, M. O. Chem. Heterocycl. Compd. 2001, 37, 1096. [Khim. Geterotsikl. Soedin. 2001, 1195.]

For this article in the English edition, see DOI https://doi.org/10.1023/A:1013223531612

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Published

2001-09-25

Issue

No. 9 (2001)

Section

Original Papers