Synthesis of substituted 4-acetylamino-4-phenylpiperidines from the corresponding 4-piperidols under Ritter reaction conditions

Authors

  • T. Д. Соколова M. V. Lomonosov State Academy of Fine Chemical Technology, Moscow 117571
  • Г. В. Черкаев M. V. Lomonosov State Academy of Fine Chemical Technology, Moscow 117571
  • И. П. Бойко M. V. Lomonosov State Academy of Fine Chemical Technology, Moscow 117571
  • А. C. Московкин M. V. Lomonosov State Academy of Fine Chemical Technology, Moscow 117571

Abstract

The reaction of substituted 4-phenyl-4-piperidols with acetonitrile under Ritter reaction conditions leads to formation of mixtures of the corresponding 4-acetylamino-4-phenylpiperidines and 1,2,5,6-tetrahydropyridines, from which we isolated the target amides by fractional crystallization.

How to Cite
Sokolova, T. D.; Cherkaev, G. V.; Boiko, I. P.; Moskovkin, A. S. Chem. Heterocycl. Compd. 1997, 33, 676. [Khim. Geterotsikl. Soedin. 1997, 776.]

For this article in the English edition, see DOI https://doi.org/10.1007/BF02291798

Downloads

Published

1997-06-25

Issue

No. 6 (1997)

Section

Original Papers