Synthesis and stereochemistry of chiral 2-azetidinones and 2-azetidinethiones. 2. Study of the chiroptical properties of some 2-azetidinones

Abstract

Circular dichroism (CD) spectra were taken for 13 2-azetidinones with one, two, and three asymmetric sites. A possible correlation was found between the sign of the Cotton effect (CE) of the n-π* transition of the amide chromophore with the absolute configuration of the endocyclic stereocenters of 3-methyl-, 4-methyl-, and 3,4-dimethyl-2-azetidinones both with and without an achiral N-α,α-dimethylbenzyl or chiral N-α-methylbenzyl substituent.

How to Cite
Dunina, V. V.; Romanova, N. N. Chem. Heterocycl. Compd. 1995, 31, 922. [Khim. Geterotsikl. Soedin. 1995, 1059.]

For this article in the English edition, see DOI https://doi.org/10.1007/BF01170320