Synthesis and properties of derivatives of <i>sym</i>-triazine. 15. Synthesis of amine derivatives of <i>sym</i>-triazine that contain indole groups

Abstract

By the cyclocondensation of imino esters of acids of the indole series with N-acylguanidines, 2-amino-4,6-disubstituted sym-triazines are obtained that contain indole groups. The reaction of N-(indolyl-3-imidolyl)guanidine with esters of carboxylic acids leads to 2-amino-4-(3-indolyl)-6-substituted sym-triazines. Indolyl-containing N-subsitituted 2,4-diamino-sym-triazines are synthesized by the reaction of imino esters of indole acids with biguanides. Similar products are also formed when 2-amino-4-trichloromethyl-sym-triazines that contain indole substituents react with dimethylamine, morpholine, or furfurylamine.

How to Cite
Kelarev, V. I.; Koshelev, V. N.; Morozova, G. V.; Karakhanov, R. A.; Remizov, A. S. Chem. Heterocycl. Compd. 1995, 31, 186. [Khim. Geterotsikl. Soedin. 1995, 214.]

For this article in the English edition, see DOI https://doi.org/10.1007/BF01169678