4-Thiazolidinones with cyclic substituents in the 2 position

Abstract

Cycloalkyspiro-4-thiazolidinones are synthesized by the reaction of several cyclic ketones with 2-mercaptopropionic or thioglycolic acids in the presence of an ammonium salt. The reaction of thioglycolic acid with N-benzylidene derivatives of adamantylalkylamines or hydroxyphenylethylamines leads to the corresponding N-substituted 5-phenyl-4-thiazolodinones. By the condensation of adamantanone thiosemicarbazide, or its hydroxy derivative, with chloroacetic acid, the corresponding substituted hydrazones are obtained.

How to Cite
Lavrova, L. N.; Kurkovskaya, L. N.; Yashunskii, V. G. Chem. Heterocycl. Compd. 1994, 30, 859. [Khim. Geterotsikl. Soedin. 1994, 991.]

For this article in the English edition, see DOI https://doi.org/10.1007/BF01169647