Synthesis and conversions of polyhedral compounds. 20. Synthesis of certain derivatives of 3,7-diazabycyclo[3.3.1]nonane

Abstract

1,3-Diazaadamantanes containing hydrogen atoms or a hydroxyl or oxime group at C₍₆₎, under the action of 2 moles of aralkyl halides, are converted in alkaline aqueous media to 3,7-diaralkyl-3, 7-diazabi cyclo(3.3.1]nonanes containing the indicated groups at C₍₉₎. Analogously, quaternary salts of 1,3-diaza-adamantanes containing hydrogen atoms or a hydroxyl group at C₍₆₎ are converted in an alkaline aqueous medium to the corresponding 3-alkyl-3,7-diazabicyclo[3.3.1]nonanes containing the indicated groups at C₍₉₎.

How to Cite
Minasyan, G. G.; Arutyunyan, A. D.; Adamyan, G. G.; Agadzhanyn, Ts. E. Chem. Heterocycl. Compd. 1994, 30, 353. [Khim. Geterotsikl. Soedin. 1994, 401.]

For this article in the English edition, see DOI https://doi.org/10.1007/BF01165705