Synthesis of 4,5-bifunctionally substituted imidazolidin-2-ones

Abstract

It is shown that the reaction of readily available 4,5-dihydroxyimidazolidin-2-ones with hydrazoic or p-toluenesulfinic acid takes place stereo- and regioselectively and leads to the formation of 4,5-diazido- or 4,5-di(p-tolylsulfonyl)imidazolidin-2-ones. The example of 4,5-diazidoimidazolidin-2-one is used to demonstrate the possibility of using compounds of this type for stereoselective introduction of substituents into the 4 and 5 positions of the imidazole ring.

How to Cite
Shutalev, A. D. Chem. Heterocycl. Compd. 1993, 29, 1421. [Khim. Geterotsikl. Soedin. 1993, 1645.]

For this article in the English edition, see DOI https://doi.org/10.1007/BF00531404