TRANSFORMATIONS OF COTARNINE CHLORIDE BY THE ACTION OF SILVER ACETYLIDES AND ALKYNES

Authors

  • Леонид Г. Воскресенский Peoples Friendship University of Russia
  • Александр А. Титов Российский университет дружбы народов
  • Реза Самавати Российский университет дружбы народов
  • Татьяна Н. Борисова Российский университет дружбы народов
  • Елена А. Сорокина Российский университет дружбы народов
  • Алексей В. Варламов Российский университет дружбы народов

DOI:

https://doi.org/10.1007/3113

Keywords:

cotarnine chloride, [1, 3]dioxolo[4, 5-i][3]benzazocines, 5-g]pyrrolo[2, 1-a]isoquinolines, DMAD, ethynyl methyl ketone, methyl propiolate, silver acetylides.

Abstract

Three-component reactions of cotarnine chloride with silver acetylides and methyl propiolate or ethynyl methyl ketone in acetonitrile, as well as two-component reactions of 5-phenylethynyl-substituted tetrahydro[1,3]dioxolo[4,5-g]isoquinoline with alkynes in various solvents were studied. Performing them in 2,2,2-trifluoroethanol as the solvent, 10-phenylethynyl-substituted tetrahydro[1,3]dioxolo[4,5-i][3]benzazocines were obtained in good yields.

 

Authors: Leonid G. Voskressensky, Alexander A. Titov, Reza Samavati, Tatiana N. Borisova, Elena A. Sorokina, Alexey V. Varlamov

Author Biography

Леонид Г. Воскресенский, Peoples Friendship University of Russia

Organic Chemistry Department, professor

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Published

2016-05-09

Issue

Vol. 52 No. 5 (2016)

Section

Original Papers