SYNTHESIS OF CHIRAL PHOSPHAZENE BASES

Authors

  • Martins Priede Latvian Institute of Organic Synthesis
  • Elina Priede Latvian Institute of Organic Synthesis
  • Jaan Saame Institute of Chemistry, University of Tartu
  • Ivo Leito Institute of Chemistry, University of Tartu
  • Edgars Suna Latvian Institute of Organic Synthesis

DOI:

https://doi.org/10.1007/3381

Keywords:

phosphazene base, tetraaminophosphonium salts, basicity, one-pot synthesis, pKip value

Abstract

Air-stable and crystalline tetraaminophosphonium tetrafluoroborates possessing chiral, enantiomerically pure 1,2-diamine moiety have been synthesized by a three-step sequential one-pot approach. The tetrafluoroborate salts can be purified by recrystallization or chromatography and subsequently converted to the phosphazene bases by treatment with t-BuOK. Basicity values in tetrahydrofuran have been measured for the obtained phosphazene bases by means of spectrophotometric titration.

 

 

Author Biographies

Martins Priede, Latvian Institute of Organic Synthesis

Laboratory of Advanced Technologies for Organic Synthesis. Research Assistant.

Elina Priede, Latvian Institute of Organic Synthesis

Laboratory of Advanced Technologies for Organic Synthesis. Research Scientist.

Jaan Saame, Institute of Chemistry, University of Tartu

Chemist.

Ivo Leito, Institute of Chemistry, University of Tartu

Chair of Analytical Chemistry. Professor.

Edgars Suna, Latvian Institute of Organic Synthesis

Laboratory of Advanced Technologies for Organic Synthesis. Principal Scientist.

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Published

2016-08-22

Issue

Vol. 52 No. 8 (2016)

Section

Original Papers