SYNTHESIS AND AZIDE-TETRAZOLE TAUTOMERISM OF 3-AZIDO-1,2,4-TRIAZINES

Abstract

This review provides a generalized and systematized literature data from the previous 50 years on the synthesis and azido-tetrazole equilibrium of 3-azido-1,2,4-triazines, which are capable of rearrangement to tetrazole isomers with various types of ring fusion between the azole and azine moieties. Since the cyclization of 3-azido-1,2,4-triazines can lead to the formation of both tetrazolo[5,1-c][1,2,4]-triazines and tetrazolo[1,5-b][1,2,4]triazines, a particular attention was devoted to the methods for proving the structures of the isomeric tetrazole forms.