THE REACTION OF ETHYL 2-OXO-3-(4-OXO-4<i>Н</i>-CHROMEN-2-YL)PROPANOATES WITH <i>S</i>-METHYLISOTHIOSEMICARBAZIDE HYDROIODIDE

Abstract

Ethyl 2-oxo-3-(4-oxo-4Н-chromen-2-yl)propanoates reacted with  S-methylisothiosemicarbazide hydroiodide at the ethoxalyl group,
forming 3-methylsulfanyl-6-[(4-oxo-4Н-chromen-2-yl)methyl]-1,2,4-triazin-5(2H)-ones upon refluxing in pyridine (40–50% yields) or 6-[(4-oxo-4Н-chromen-2-yl)methyl]-1,2,4-triazine-3,5(2Н,4Н)-diones when refluxed in ethanol (37–74% yields).