METHODS OF SYNTHESIS OF 2-AMINOCHROMANES

Authors

  • Кирилл С. Корженко Samara State Technical University, 244 Molodogvardeyskaya St., Samara 443100, Russia
  • Дмитрий В. Осипов Samara State Technical University, 244 Molodogvardeyskaya St., Samara 443100, Russia
  • Виталий А. Осянин Samara State Technical University, 244 Molodogvardeyskaya St., Samara 443100, Russia
  • Юрий Н. Климочкин Samara State Technical University, 244 Molodogvardeyskaya St., Samara 443100, Russia

DOI:

https://doi.org/10.1007/6076

Keywords:

2-aminochromanes, chroman-2-ols, enamides, enamines, 2-hydroxybenzaldehyde, o-quinone methide, Diels–Alder reaction, Michael reaction.

Abstract

The review summarizes the existing methods of the synthesis of 2-aminochromanes. N,O-acetals in which the dihydropyran ring is spiroannulated or condensed with any carbo- or heterocyclic fragment at the b or c bond are not considered in the review because of the wide variety of methods for their preparation. The main attention is paid to (4+2) annulation processes with the participation of o-quinone methide precursors, salicylic aldehydes and their imino derivatives, as well as substitution reactions in chroman-2-ols and conjugated addition to electron-deficient 4H-chromenes.

Author Biographies

Кирилл С. Корженко, Samara State Technical University, 244 Molodogvardeyskaya St., Samara 443100, Russia

аспирант кафедры органической химии

Дмитрий В. Осипов, Samara State Technical University, 244 Molodogvardeyskaya St., Samara 443100, Russia

к.х.н., доцент кафедры органической химии

Виталий А. Осянин, Samara State Technical University, 244 Molodogvardeyskaya St., Samara 443100, Russia

д.х.н., профессор кафедры органической химии

Юрий Н. Климочкин, Samara State Technical University, 244 Molodogvardeyskaya St., Samara 443100, Russia

д.х.н., профессор, заведующий кафедрой органической химии

Published

2021-03-15

Issue

Section

Review Articles