SYNTHESIS OF SOME NEW NITROGEN BRIDGE-HEAD PYRIDO[1,2,4]TRIAZEPINES

Abstract

Ring closure reactions of 1,6-diamino-4-(4-chlorophenyl)-2-oxopyridine-3,5-dicarbonitrile with various 1,3-dielectrophiles, namely, diethyl malonate, ethyl ethoxymethylenecyanoacetate, 2-cyano-3,3-bis(methylthio)acrylonitrile, dimethyl acetylene-dicarboxylate, dehydroacetic acid, chromone-3-carbonitrile, and 3-formylchromone led to the formation of the target biheterocyclic 1,2,4-triazepines. The reactions of 3-phenyl- azo-2,4-pentadione, ethyl α-cyano-α-phenylazoacetate, and 3,1-benzoxazin-4-one deri-vative with  compound 1 are also described.

How to Cite
Abdel-Megid, M. Chem. Heterocycl. Compd. 2009, 45, 1523. [Khim. Geterotsikl. Soedin. 2010, 1888.]

For this article in the English edition see DOI 10.1007/s10593-010-0460-y