INTERACTION OF SECONDARY AMINES WITH AROMATIC ALDEHYDES – EFFICIENT METHOD FOR SYNTHESIS OF THE FUNCTIONALIZED HETEROCYCLIC AMINES

Authors

  • Ж. В. Игнатович Institute of the Chemistry of New Materials, National Academy of Sciences of Belarus, Minsk 220141
  • К. Н. Гусак Institute of the Chemistry of New Materials, National Academy of Sciences of Belarus, Minsk 220141
  • Т. В. Чернихова Institute of the Chemistry of New Materials, National Academy of Sciences of Belarus, Minsk 220141
  • Н. Г. Козлов Institute of Physical Organic Chemistry, National Academy of Sciences of Belarus, Minsk 220072
  • Е. В. Королева Institute of the Chemistry of New Materials, National Academy of Sciences of Belarus, Minsk 220141

DOI:

https://doi.org/10.1007/7314

Keywords:

N-methylpiperazine, benzaldehyde derivatives, formic acid, pyrrolidine, reductive amination

Abstract

A method is proposed for the benzylation of  secondary heterocyclic amines with functionalized derivatives of benzaldehyde in the presence of formic acid under conditions close to amination according to the Leuckart–Wallach reaction.

How to Cite
Ignatovich, Zh. V.; Gusak, K. N.; Chernikhova, T. V.; Kozlov, N. G.; Koroleva,  E. V.  Chem. Heterocycl. Compd. 2007, 43, 1540. [Khim. Geterotsikl. Soedin. 2007, 1820.]

For this article in the English edition see DOI 10.1007/s10593-007-0238-z

 

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Published

2023-01-16

Issue

No. 12 (2007)

Section

Original Papers