Acyclic analogs of pyrimidine nucleosides. Synthesis of 1-(2-hydroxyethoxymethyl)- and 1-(4-hydroxybutyl)-5-amino derivatives of uracil

Authors

  • M. C. Новиков Scientific-Research Institute of Pharmacology, Volgograd Medical Academy, Volgograd 400066
  • А. А. Озеров Scientific-Research Institute of Pharmacology, Volgograd Medical Academy, Volgograd 400066

Abstract

With the objective of discovering new antiviral agents based on acyclic analogs of pyrimidine nucleosides, we have synthesized 1-(2-hydroxyethoxymethyl)- and 1-(4-hydroxybutyl) derivatives of uracil having various aromatic and heterocyclic amino-containing substituents in the 5 position of the pyrimidine ring.

How to Cite
Novikov, M. S.; Ozerov, A. A. Chem. Heterocycl. Compd. 1998, 34, 841. [Khim. Geterotsikl. Soedin. 1998, 34, 971.]

For this article in the English edition, see DOI https://doi.org/10.1007/BF02251694

Published

1998-07-25

Issue

Section

Original Papers