ONE-POT TRANSFORMATIONS OF TETRACYANOCYCLOPROPANES INTO HIGHLY FUNCTIONALIZED PYRIDINES

Authors

  • Анастасия И. Ершова Chuvash State University named after I. N. Ulyanov, 15 Moskovskiy Ave., Cheboksary 428015, Russia
  • Олег Е. Насакин Chuvash State University named after I. N. Ulyanov, 15 Moskovskiy Ave., Cheboksary 428015, Russia
  • Олег В. Ершов Chuvash State University named after I. N. Ulyanov, 15 Moskovskiy Ave., Cheboksary 428015, Russia

DOI:

https://doi.org/10.1007/7778

Keywords:

cyclopropane, nitriles, polycyano compounds, pyridine, one-pot synthesis, recyclization.

Abstract

An effective method has been developed for the synthesis of 2-amino-4-aryl-6-chloropyridine-3,5-dicarbonitriles from 3-arylcyclopropane-1,1,2,2-tetracarbonitriles by treating the starting materials with sodium hydride in anhydrous DMF, followed by HCl in isopropanol.

 

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Published

2023-09-04

Issue

Vol. 59 No. 8 (2023)

Section

Short Communications