NEW SIMPLE AND ONE-POT SYNTHETIC ROUTES TO POLYFUNCTIONALLY SUBSTITUTED IMIDAZO[1,2-<i>a</i>]PYRIDINES, PYRIDO[1,2-<i>a</i>]PYRIMIDINES, PYRIDO[1,2-<i>a</i>]-1,3-DIAZEPINES, AND IMIDAZO[1,2-<i>a</i>]PYRIMIDINES

Authors

  • M. Hammouda Department of Chemistry, Faculty of Science, University of Mansoura, Mansoura
  • Z. M. Abou Zeid Department of Chemistry, Faculty of Science, University of Mansoura, Mansoura
  • M. A. Metwally Department of Chemistry, Faculty of Science, University of Mansoura, Mansoura

DOI:

https://doi.org/10.1007/8118

Keywords:

arylidenemalononitriles, nitroenamines, Mannich reaction

Abstract

Reactions  of arylidenemalononitriles with  2-nitromethylene-substituted imidazolidine, hexahydropyrimidine   and  hexahydro-1,3-diazepine afforded the  title derivatives. Reaction of 2-nitromethylenehexahydropyrimidine  with benzylamine or  n-butylamine and formalin in a molar  ratio of 1:1:2 gave the hexahydro-1H-imidazo[1,2-c]pyrimidine derivatives. Treatment of 2-nitro- methyleneimidazolidine and hexahydropyrimidine with secondary aliphatic amines  and formalin in a molar ratio of 1:1:1 afforded corresponding methylene bis-compounds.

How to Cite
Hammouda, M.; Abou Zeid, Z. M.; Metwally, M. A.  Chem. Heterocycl. Compd. 2005, 41, 1525. [Khim. Geterotsikl. Soedin. 2005, 1850.]

For this article in the English edition, see DOI 10.1007/s10593-006-0031-4

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Published

2023-10-13

Issue

No. 12 (2005)

Section

Original Papers