SYNTHESIS AND SOME TRANSFORMATIONS OF 2-(3-AMINO-1-PHENYLPROPYL)FURAN

Authors

  • Н. С. Арутюнян A. L. Mndzhoyan Institute of Fine Organic Chemistry, National Academy of Sciences of the Republic of Armenia, Erevan
  • Л. А. Акопян A. L. Mndzhoyan Institute of Fine Organic Chemistry, National Academy of Sciences of the Republic of Armenia, Erevan
  • Г. А. Геворгян A. L. Mndzhoyan Institute of Fine Organic Chemistry, National Academy of Sciences of the Republic of Armenia, Erevan
  • Г. М. Снхчян A. L. Mndzhoyan Institute of Fine Organic Chemistry, National Academy of Sciences of the Republic of Armenia, Erevan
  • Г. А. Паносян Molecular Structure Research Center, National Academy of Sciences of the Republic of Armenia, Erevan 375014

DOI:

https://doi.org/10.1007/8317

Keywords:

2-(3-amino-1-phenylpropyl)furan, ethyl furfurylidenecyanoacetate, ethyl α-cyano-β-(2-furyl)hydrocinnamate, reduction, decarbethoxylation

Abstract

A preparative method was developed for the synthesis of ethyl furfurylidenecyanoacetate. Its condensation with phenylmagnesium bromide gave ethyl  α-cyano-β-(2-furyl)hydrocinnamate, the decarboxylation of which led to  β-(2-furyl)hydrocinnamonitrile. Reduction of this nitrile with lithium aluminum hydride gave 2-(3-amino-1-phenylpropyl)furan. Some of its transformations were studied.

How to Cite
Arutyunyan, N. S.; Akopyan, L. A.; Gevorgyan, G. A.; Snkhchyan, G. M.; Panosyan, G. A.  Chem. Heterocycl. Compd. 2005, 41, 437. [Khim. Geterotsikl. Soedin. 2005, 517.]

For this article in the English edition, see DOI 10.1007/s10593-005-0166-8

 

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Published

2023-11-16

Issue

No. 4 (2005)

Section

Original Papers