THIAZOLECARBOXYLIC ACID DERIVATIVES. 1. N-SUBSTITUTED 2-AMINO-4-METHYLTHIAZOLE-5-CARBOXYLIC ACID DERIVATIVES

Authors

  • В. В. Довлатян Armenian Agricultural Academy, Yerevan 375009
  • К. А. Элиазян Armenian Agricultural Academy, Yerevan 375009
  • В. А. Пивазян Armenian Agricultural Academy, Yerevan 375009
  • Э. А. Казарян Armenian Agricultural Academy, Yerevan 375009
  • А. П. Енгоян Armenian Agricultural Academy, Yerevan 375009

Keywords:

aminoformiminothiazole, acylaminoformiminothiazole, dimethylaminoformiminothiazole, thiazole-5-carboxylic acid, thiazole-5-carboxylate esters

Abstract

Acylation of the ethyl ester and anilide of 2-amino-4-methylthiazole-5-carboxylic acid gave 2-acetyl(arylsulfonyl)amino derivatives. Methylation of acetylaminothiazole and subsequent deacetylation gave 2-methylamino-4-methylthiazole-5-carboxylic acid, which was then converted into esters. The ethyl ester and anilide of thiazole-2-carboxylic acid were used as starting compounds for the synthesis of 2-dimethylaminoformimino- and 2-chlorobenzenesulfonylureido derivatives.

How to Cite
Dovlatyan, V. V.; Eliazyan, K. A.; Pivazyan, V. A.; Kazaryan, E. A.; Engoyan, A. P. Chem. Heterocycl. Compd. 2004, 40, 84. [Khim. Geterotsikl. Soedin. 2004, 90.]

For this article in the English edition, see DOI 10.1023/B:COHC.0000023773.23834.ba

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Published

2004-01-25

Issue

No. 1 (2004)

Section

Original Papers