PREPARATION OF BENZISOTHIAZOLONES FROM 2-BROMOBENZAMIDES AND SULFUR UNDER COPPER CATALYSIS CONDITIONS
DOI:
https://doi.org/10.1007/889Keywords:
benzisothiazolone, 2-bromobenzamide, sulfur, copper catalysis, S–N bondAbstract
A convenient two-stage method has been developed for preparing benz[d]isothiazol-3(2H)-ones from 2-bromobenzamides and sulfur in a one-pot process under copper catalysis conditions. The method is suitable for the synthesis of N-aryl-, benzyl-, and alkyl-substituted benzisothiazolones. The yields of the benzisothiazolones depend on the nature of the starting amide and can reach 91%.
Authors: V. Krasikova and M. Katkevics
English Translation in Chemistry of Heterocyclic Compounds, 2012, 48 (11), pp 1684-1690
http://link.springer.com/article/10.1007/s10593-013-1193-5