TRISUBSTITUTED 1,3,5-TRIAZINES. 5. REACTION OF 2,4,6-TRIS[DI(<i>tert</i>-BUTOXYCARBONYL)NITROMETHYL]-1,3,5-TRIAZINE WITH NUCLEOPHILES
Keywords:
di(tert-butoxycarbonyl)nitromethyl group, 2,4,6-tris[di(tert-butoxycarbonyl)nitromethyl]-1,3,5-triazine, nucleophilic substitution, nucleophilic reagentsAbstract
The reaction of 2,4,6-tris[di(tert-butoxycarbonyl)nitromethyl]-1,3,5-triazine with ammonia, amines, and hydrazine has been studied. It was possible to substitute one of the di(tert-butoxycarbonyl)nitromethyl groups in this compound in the presence of ammonia, primary aliphatic amines, dimethylamine, and morpholine. The reaction with hydrazine leads to both mono- and disubstituted products. A double dealkoxylation occurs in the presence of diethylamine to give the bis(dimethylammonium) salt of 2,4-bis(tert-butoxycarbonylnitromethyl)-6-[di(tert-butoxycarbonyl)nitromethyl]-1,3,5-triazine.
How to Cite
Kalvinsh, I.; Stradins, J.; Skorova, A. Chem. Heterocycl. Compd. 2003, 39, 624. [Khim. Geterotsikl. Soedin. 2003, 722.]
For this article in the English edition, see DOI https://doi.org/10.1023/A:1025150216863
