SYNTHESIS AND STUDY OF LACTIM ETHERS OF 3,4-DIHYDROCARBOSTYRYL AND 2,3,4,5-TETRAHYDROBENZ[<i>b</i>]AZEPIN-2-ONE

Authors

  • Т. В. Головко NIOPIK State Scientific Center of the Russian Federation, Moscow 103787
  • Н. П. Соловьева Scientific Research Chemical-Pharmaceutical Institute, Moscow 119815
  • О. С. Анисимова Scientific Research Chemical-Pharmaceutical Institute, Moscow 119815
  • В. Г. Граник NIOPIK State Scientific Center of the Russian Federation, Moscow 103787

Keywords:

dihydrocarbostyryl, lactim ether, tetrahydrobenz[b]azepinone, triethyloxonium fluoborate, alkylation

Abstract

Alkylation of 3,4-dihydrocarbostyryl and 2,3,4,5-tetrahydrobenz[b]azepin-2-one using dimethyl sulfate and triethyloxonium fluoborate gives the corresponding lactim ethers. The reactions of lactim ethers with different compounds having primary amino groups (including ammonia, alkyl-, aralkyl-, and arylamines, amino acids, and related compounds) have been studied. Novel heterocyclic compounds based on the lactim ethers have been synthesized.

How to Cite
Golovko, T. V.; Solov'eva, N. P.; Anisimova, O. S.; Granik, V. G. Chem. Heterocycl. Compd. 2003, 39, 344. [Khim. Geterotsikl. Soedin. 2003, 389.]

For this article in the English edition, see DOI https://doi.org/10.1023/A:1023918911369

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Published

2003-03-25

Issue

No. 3 (2003)

Section

Original Papers