Synthesis of 2,6-diamino-3,5-dicyano-4-ethyl-4H-thiopyran and its recyclization to 6-amino-3,5-dicyano-4-ethylpyridine-2(1H)-thione

Authors

  • B. Д. Дяченко T. G. Shevchenko Lugansk State Pedagogical Institute, Lugansk 348011
  • C. Г. Кривоколыско T. G. Shevchenko Lugansk State Pedagogical Institute, Lugansk 348011
  • В. П. Литвинов N. D. Zelinskii Institute of Organic Chemistry, Russian Academy of Sciences, 117913 Moscow

Abstract

The triple condensation of propionaldehyde, malononitrile, and cyanothioacetamide gives 2,6-diamino-3,5-dicyano-4-ethyl-4H-thiopyran, which recyclizes to give 6-amino-3, 5-dicyano-4-ethylpyridine-2(1H)-thione. This thione was used to synthesize substituted 2-alkylthiopyridines and the corresponding thieno[2,3-b]pyridines.

How to Cite
Dyachenko, V. D.; Krivokolysko, S. G.; Litvinov, V. P. Chem. Heterocycl. Compd. 1996, 32, 947. [Khim. Geterotsikl. Soedin. 1996, 1099.]

For this article in the English edition, see DOI https://doi.org/10.1007/BF01176972

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Published

1996-08-25

Issue

No. 8 (1996)

Section

Original Papers