CATION-EXCHANGE RESIN AS AN EFFICIENT HETEROGENEOUS CATALYST FOR ONE-POT THREE-COMPONENT SYNTHESIS OF 2,3-DIHYDRO-4(1<i>H</i>)-QUINAZOLINONES

Авторы

  • M. Wang College of Chemistry, Chemical Engineering and Food Safety, Bohai University
  • T. T. Zhang College of Chemistry, Chemical Engineering and Food Safety, Bohai University
  • J. J. Gao College of Chemistry, Chemical Engineering and Food Safety, Bohai University
  • Y. Liang College of Chemistry, Chemical Engineering and Food Safety, Bohai University

DOI:

https://doi.org/10.1007/1165

Ключевые слова:

2, 3-dihydro-4(1H)-quinazolinones, isatoic anhydride, cation-exchange resin, multicomponent reactions

Аннотация

Various mono- and disubstituted 2,3-dihydro-4(1H)-quinazolinones were synthesized efficiently by a one-pot three-component condensation of isatoic anhydride, aromatic aldehydes, and ammonium salts or primary amines using a strong acidic cation-exchange resin as the catalyst in EtOH–H2O solution. The catalyst is cheap, efficient, stable, and reusable under the reaction conditions. The novel method offers several advantages, such as excellent yields, environmentally friendly reaction media, and simple procedure.

Also published in Chemistry of Heterocyclic Compounds, 2012, 48 (6), pp 897-902

http://link.springer.com/article/10.1007/s10593-012-1073-4

Загрузки

Опубликован

2013-11-15

Выпуск

№ 6 (2012)

Раздел

Оригинальные статьи