Fe<sub>3</sub>O<sub>4</sub> NANOPARTICLES AS AN EFFICIENT AND REUSABLE CATALYST FOR THE SOLVENT‐FREE SYNTHESIS OF 1<i>H</i>-INDOLE AND 1<i>H</i>-PYRROLE DERIVATIVES
DOI:
https://doi.org/10.1007/3163Ключевые слова:
activated acetylenic compounds, ethyl 2-chloroacetoacetate, Fe3O4 nanoparticles, green synthesisАннотация
Magnetic Fe3O4 nanoparticles as a heterogeneous catalyst were found to be efficient for the synthesis of a series of pyrrole and indole derivatives using three-component reactions of primary amines, 1,3-dicarbonyl compounds, and activated acetylenic compounds under solvent-free conditions at room temperature. The present protocol offers the advantages of clean reaction, short reaction time, high yield, easy purification, and affordability of the catalyst.
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Опубликован
2016-06-02
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Оригинальные статьи