STUDY ON THE SCALE-UP OF PHASE-TRANSFER-CATALYZED AZO COUPLING REACTIONS IN FLOW REACTORS

Авторы

  • Faith Akwi Nelson Mandela Metropolitan University, P. O. Box 77 000, University Way, Port Elizabeth, 6031
  • Paul Watts Nelson Mandela Metropolitan University, P. O. Box 77 000, University Way, Port Elizabeth, 6031

DOI:

https://doi.org/10.1007/3401

Ключевые слова:

heterocycles, azo coupling, flow chemistry, microreactors

Аннотация

We report the first systematic study on the channel size effect in various microreactor systems on the efficiency of phase-transfer-catalyzed azo coupling reactions. The optimum scaled-up channel diameter was 0.5 mm, which facilitated the synthesis of diazo compounds in high yields.

 

Загрузки

Опубликован

2016-12-01

Выпуск

Том 52 № 11 (2016): Неклассические методы активации в химии гетероциклов

Раздел

Оригинальные статьи