SYNTHESIS OF SEVEN-MEMBERED NITROGEN HETEROCYCLES THROUGH THE UGI MULTICOMPONENT REACTION

Авторы

  • Luca Banfi Department of Chemistry and Industrial Chemistry, University of Genova, via Dodecaneso, 31, Genova 16146
  • Andrea Basso Department of Chemistry and Industrial Chemistry, University of Genova, via Dodecaneso, 31, Genova 16146
  • Chiara Lambruschini Department of Chemistry and Industrial Chemistry, University of Genova, via Dodecaneso, 31, Genova 16146
  • Lisa Moni Department of Chemistry and Industrial Chemistry, University of Genova, via Dodecaneso, 31, Genova 16146
  • Renata Riva Department of Chemistry and Industrial Chemistry, University of Genova, via Dodecaneso, 31, Genova 16146

DOI:

https://doi.org/10.1007/3705

Ключевые слова:

azepines, benzazepines, benzodiazepines, diazepines, oxazepines, thiazepines, multicomponent reactions, Ugi reaction

Аннотация

This paper reviews all the syntheses of 7-membered nitrogen heterocycles that are based on the Ugi multicomponent reaction. Different systems may be obtained in a diversity-oriented manner employing three general strategies: i) intramolecular Ugi reaction; ii) Ugi reaction followed by cyclization involving one additional functional group; iii) Ugi reaction followed by cyclization involving two additional functional groups.

Опубликован

2017-05-11