(AZA)INDOLIZINES AND ETHYL PROPIOLATE: [8+2] AND [1,10] CYCLIZATIONS

Авторы

  • Eugene V. Babaev МГУ
  • Ivan A. Shadrin Lomonosov Moscow State University, 1 Leninskie Gory, Moscow 119991
  • Victor B. Rybakov Lomonosov Moscow State University, 1 Leninskie Gory, Moscow 119991

DOI:

https://doi.org/10.1007/4509

Ключевые слова:

[8 2] cycloaddition, indolizine, imidazo[1, 2-a]pyridine, Sonogashira reaction

Аннотация

(Aza)indolizines reacted with ethyl propiolate regioselectively forming (aza)[2.2.3]cyclazines. The Sonogashira reaction of 5-iodo(aza)indolizines and acetylenes led to 5-ethynyl(aza)indolizines. In the case of indolizine derivative the by-product was ethynylcyclazine. The structures of [2.2.3]cyclazines were proved by X-ray structural analysis.

Биография автора

Eugene V. Babaev, МГУ

Prof.

Загрузки

Опубликован

2018-05-16

Выпуск

Том 54 № 3 (2018): Металлокаталитические синтезы гетероциклов

Раздел

Оригинальные статьи