ACTIVATION-FREE ONE-POT ALKYNYLATION–CYCLIZATION SYNTHESIS OF 2-SUBSTITUTED 4-AZAINDOLES AND INDOLES

Авторы

  • Thomas J. J. Müller Heinrich Heine University Düsseldorf Institute of Organic Chemistry and Macromolecular Chemistry
  • Timo Lessing Institut für Organische Chemie und Makromolekulare Chemie, Lehrstuhl für Organische Chemie, Heinrich-Heine-Universität Düsseldorf

DOI:

https://doi.org/10.1007/4516

Ключевые слова:

4-azaindoles, heterocycles, indoles, alkynylation, cyclization, one-pot reaction.

Аннотация

2-Substituted 4-azaindoles and indoles are rapidly and efficiently prepared in an activation-free Pd-catalyzed alkynylation–cyclization sequence starting from 3-amino-2-bromopyridine or o-bromoaniline and terminal alkynes in a one-pot fashion.

Биография автора

Thomas J. J. Müller, Heinrich Heine University Düsseldorf Institute of Organic Chemistry and Macromolecular Chemistry

Institute of Organic Chemistry and Macromolecular Chemistry, chair of organic chemistry, director of institute

Загрузки

Опубликован

2018-05-15

Выпуск

Том 54 № 3 (2018): Металлокаталитические синтезы гетероциклов

Раздел

Оригинальные статьи