GREEN SYNTHESIS OF NOVEL PHOSPHONATE DERIVATIVES USING ULTRASONIC IRRADIATION

Авторы

  • Shirin Sharafian Department of Chemistry, Qaemshahr Branch, Islamic Azad University, Qaemshahr, Iran
  • Zinatossadat Hossaini Department of Chemistry, Qaemshahr Branch, Islamic Azad University, Qaemshahr, Iran
  • Faramarz Rostami-Charati Department of Chemistry, Qaemshahr Branch, Islamic Azad University, Qaemshahr, Iran Research Center for Conservation of Culture Relics, Research Institute of Cultural Heritage & Tourism, Tehran, Iran
  • Mohammad A. Khalilzadeh Department of Chemistry, Qaemshahr Branch, Islamic Azad University, Qaemshahr, Iran

DOI:

https://doi.org/10.1007/5460

Ключевые слова:

euparin, isatin, primary amines, multicomponent reaction, ultrasonic irradiation.

Аннотация

A novel and efficient procedure for the generation of quinazolinone phosphonate derivatives employing the reaction of euparin, isatin or
its derivatives, primary amines, dialkyl acetylenedicarboxylates, trimethyl phosphite or triphenyl phosphite, and acidic solution of hydrogen peroxide in aqueous media at ambient temperature under ultrasonic irradiation was developed. Without ultrasonic irradiation, the reaction does not proceed and agitation of the reaction mixture is difficult. Some advantages of this procedure are: short time of reaction, high yields of products, easy isolation of products.

Опубликован

2020-11-05

Выпуск

Раздел

Оригинальные статьи